Compact laser powers novel x-ray device for advanced medical imaging, other uses

Nov. 26, 2013
Using a compact yet powerful laser, a research team at the University of Nebraska-Lincoln has developed a new way to generate synchrotron x-rays, which are high enough in quality for advanced medical imaging, among other applications.

Using a compact yet powerful laser, a research team at the University of Nebraska-Lincoln's Extreme Light Laboratory has developed a new way to generate synchrotron x-rays, which are high enough in quality for advanced medical imaging, among other applications. Until now, access to the technology has been limited, as most traditional synchrotron x-ray devices are gigantic, expensive, and available only at a few sites around the world.

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Physics professor Donald Umstadter, director of the Extreme Light Laboratory, led the research project. He compares the synchrotron x-ray breakthrough to the development of personal computers, giving more people access to computing power once available only via large and costly mainframe computers. Shrinking components of advanced laser-based technology will increase the feasibility of producing high-quality x-rays in medical and university research laboratories, which in turn could lead to new applications for the x-rays, he says.

Doctoral student Nathan Powers displays the electron accelerator used to generate x-ray light. (Both photos courtesy of Greg Nathan/University Communications)

Because the new x-ray device could be small enough to fit in a hospital or on a truck, it could lead to more widespread applications for advanced x-ray technology, including the ability to find cancerous tumors at earlier stages, study extremely fast reactions that occur too rapidly for observation with conventional x-rays, or detect nuclear materials concealed within a shielded container.

Though synchrotron x-rays result in lower doses of radiation as well as high-quality images, the tens of thousands of compact x-ray devices currently in operation in hospitals or at ports worldwide produce lower-quality x-rays.

In traditional synchrotron machines, electrons are accelerated to extremely high energy and then made to change direction periodically, leading them to emit energy at x-ray wavelength. At the European Synchrotron Radiation Facility (Grenoble, France), the electrons circle near the speed of light in a storage ring of 844 m in circumference. Magnets are used to change the direction of the electrons and produce x-rays.

Physics professor Donald Umstadter, project director, and doctoral student Nathan Powers, first author, are part of a research team that has created a laser-driven synchrotron x-ray device.

Pursuing an alternative approach in the recent experiments, the UNL team replaced both the electron accelerator and the magnets with laser light. They first focused their laser beam onto a gas jet, creating a beam of relativistic electrons. They then focused another laser beam onto the accelerated electron beam. This rapidly vibrated the electrons, which in turn caused them to emit a bright burst of synchrotron x-rays—a process referred to as Compton scattering. Remarkably, the light's photon energy was increased during this process by a million-fold. And yet, the combined length of the accelerator and synchrotron was less than the size of a dime.

"The x-rays that were previously generated with compact lasers lacked several of the distinguishing characteristics of synchrotron light, such as a relatively pure and tunable color spectrum," Umstadter says. "Instead, those x-rays resembled the 'white light' emitted by the sun."

The new laser-driven device produces x-rays over a much larger range of photon energies, extending to the energy of nuclear gamma rays. Even fewer conventional synchrotron x-ray sources are capable of producing such high photon energy.

Key to the breakthrough was finding a way to collide the two micro-thin beams—the scattering laser beam and the laser-accelerated electron beam.

"Our aim and timing needed to be as good as that of two sharpshooters attempting to collide their bullets in midair," Umstadter says. "Colliding our 'bullets' might have even been harder, since they travel at nearly the speed of light."

Full details of the team's work appear in the journal Nature Photonics; for more information, please visit http://dx.doi.org/10.1038/nphoton.2013.314.

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