Correlative microscopy system by Leica Microsystems

The Leica EM Cryo CLEM system from Leica Microsystems (Vienna, Austria), which facilitates correlative light and electron microscopy (CLEM), consists of a fluorescence microscope with cryo stage, cryo objective, and a cryo transfer shuttle. For the system, the company developed a commercially available HCX PL APO 50x / 0,90 cryo CLEM objective to enable localizing of fluorescent-labeled target structures up to 100 nm. A transfer shuttle keeps the sample under cryo conditions and contamination-free throughout the workflow.

For more information, please visit www.leica-microsystems.com.