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    • Arnaud Lepert

    General Manager, HOPS Business Unit at Coherent

    Arnaud Lepert is General Manager, HOPS Business Unit at Coherent (Santa Clara, CA).

    FIGURE 1. Principle of STED. a) Schematic drawing of the setup of a STED nanoscope with phase plate, objective lens dichroic mirror (DC), fluorescence filter (F), detector, scanning device and excitation, and STED lasers with their focal intensity distribution (right) and a representative, sub-diffraction-sized observation area. b) STED nanoscopy is based on inhibiting fluorescence emission by de-exciting the excited S1 state to the S0 ground state via stimulated emission. The probability to switch off fluorophores is increased with increasing STED power. c) This power dependence delivers sub-diffraction-sized observation volumes: The volume in which fluorescence emission is still allowed (green, insets) decreases with increasing STED laser power.
    Research

    BIOPHOTONICS: Super-resolution STED microscopy advances with yellow CW OPSL

    Matthias Schulze
    Jan. 1, 2012
    The low noise of a 577 nm CW optically pumped semiconductor laser enables researchers to image cellular structures and membrane dynamics with unprecedented resolution using blue...
    FIGURE 1. In an optically pumped semiconductor laser, a diode array pumps the front surface of the semiconductor chip. The chip's output is coupled into an external cavity, which enables intracavity doubling or tripling of the fundamental output.
    Lasers & Sources

    OPTICALLY PUMPED SEMICONDUCTOR LASERS: Green OPSLs poised to enter scientific pump-laser market

    Marco Arrigoni
    Sept. 28, 2009
    The advent of stand-alone 532 nm optically pumped semiconductor lasers delivering 2 and 5 W provides an attractive new option for pumping Ti:sapphire-based femtosecond systems...