Highlights

(Courtesy of Harsharan Singh Bhatia and Ali Ertürk, Helmholtz Munich)
Aortic regions of a human heart whose vascular plaques have been analyzed by DISCO-MS, a 3D spatial-omics technology that uses robotics to acquire proteomics data from cells identified early in diseases.
Bio&Life Sciences

Spatial-omics explores cellular organization and interactions within tissues

Feb. 15, 2023
Using spatial-omics, researchers could detect and analyze disease biomarkers at early stages of development, ultimately leading to quicker, more effective treatments.
(Courtesy of Johns Hopkins University)
With their new technique, the researchers viewed a zebrafish larvae, capturing whole-body volumetric recordings of its neural activity.
Bio&Life Sciences

Mesoscopic imaging method offers unprecedented cell views

Jan. 19, 2023
A new type of light-sheet microscopy provides a more comprehensive, distinct look than ever before at natural cell interactions.
(Courtesy of Agilent Technologies)
Cell Metabolism
Bio&Life Sciences

Activating immune cell metabolism via solid-state sensors

Nov. 14, 2022
Immune cell metabolism plays a central role in building next-generation cell therapies using solid-state sensors.
Tomocube Squid Reflectins
Fluorescence

Optical refractive index of live cells could have use as molecular probes

By changing this intrinsic physical property of the cell, microscopists could soon be using the refractive indices of live cells as molecular probes.
The Organoid Counting Software Analyzes A Single Image In Less Than Three Seconds
Cell Biology

CytoSMART Technologies develops automated organoid counter

The automated organoid counter application detects organoids using bright-field image analysis.
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Microscopy

Microscope uses machine learning to optimize illumination settings

The microscope adapts its lighting angles, colors, and patterns while teaching itself the optimal settings needed to complete a given diagnostic task.
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Microscopy

Label-free multimodal imaging system distinguishes between cell types

The label-free multimodal imaging platform enables the study of cell cultures noninvasively without the need of any contrast agent.
Deep+z 1170 783
Fluorescence

Deep learning converts 2D fluorescence microscopy images into 3D

Using a deep learning approach, researchers improved upon fluorescence microscopy to turn 2D images into stacks of virtual 3D slices showing activity inside organisms.
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Cell Biology

Engineered cells responsive to light shown to enhance insulin production

The light-switchable cells are designed to compensate for the lower insulin production or reduced insulin response found in diabetic individuals.