Highlights

(Courtesy of J. Chen et al., Nat. Methods; doi:10.1038/s41592-023-01820-3)
FIGURE 1. An optomechanical design of the SMURF two-photon microscope.
July 13, 2023
An approach to imaging electrical activity deep in the brain makes neurological studies more effective and less invasive.
(Courtesy of Anna Maria Reuss, Fabian Voigt)
Detailed image of neurons in a mouse brain, as captured using the Schmidt objectives.
May 22, 2023
Drawing inspiration from the uniqueness of scallop eyes, neuroscientists in Switzerland have developed microscope objectives that could make imaging samples simpler, cheaper, ...
(Courtesy of Ian Shih, UNC School of Medicine)
FIGURE 1. The experimental fMRI-fiber photometry platform could offer a deeper understanding of the dynamic properties of brain states and their relationship to behaviors.
April 24, 2023
An optical fiber-based platform may lead to brain network-based treatment regimens for neuropsychiatric and neurological disorders.
(Courtesy of Salk Institute)
Salk researchers developed two wearable microscopes to image cellular activity in previously inaccessible regions of the spinal cord of moving mice in real time.
April 5, 2023
Two tiny wearable microscopes for mice are generating high-resolution, high-contrast, multicolor images in real time—providing insight into signaling patterns within spinal cords...
(Courtesy of Osaka Metropolitan University)
A new system allows researchers to control a nematode worm with light-sensitive proteins (opsins) triggered by white, UV, and green.
Jan. 18, 2023
A new optogenetics-based system using various wavelengths of light is poised to significantly accelerate bio-related research.

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(Courtesy of Abraham Beyene, Howard Hughes Medical Institute Janelia Research Campus)
A schematic of DopaFilm shows spatially resolved hotspots of activity (top) and DopaFilm’s fluorescent nanosensors glow brighter when exposed to dopamine (bottom).
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The nanoprobes could show how neural circuits function at an unprecedented scale by monitoring large numbers of individual neurons simultaneously.
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Sept. 30, 2019
Using a fluorescence method, researchers have found a way to track the formation of soluble amyloid beta peptide aggregates implicated in the onset of Alzheimer's disease.