• IDEX Health & Science | Semrock

    West Henrietta, NY 14586

    COMPANY OVERVIEW

    About IDEX Health & Science | Semrock

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    1180 John St
    West Henrietta, NY 14586
    United States
    https://www.idex-hs.com/semrock
    1-585-625-5000

    More Info on IDEX Health & Science | Semrock

    Manufactures high performance and reliability optical filters tailored for biotechnology and analytical instrumentation. Utilizes ion beam sputtering exclusively, making filters that will not degrade, be sensitive to humidity, or burn out. Routinely manufactures in volume, providing OEM customers with dependable supplies, and catalog customers with an extensive in-stock selection.

    Articles

    Idex Health & Science
    The Semrock Avant filter set family includes the UFP/Venus, Cy3/Alexa Fluor 555, TyRed/AlexaFluor 594, Cy5.5/Alexa Fluor 680, Alexa Fluor 700, and Cy7/Alexa Fluor 750.
    Microscope design without oculars is greatly simplified (a); Etaluma’s optics module is shown (b).
    Advances in microscope components—lighting, filters, and cameras—are creating a paradigm shift in system design, with far-reaching impact.
    FIGURE 1. Multicolor switched excitation and emission light paths in a fluorescence microscope differ according to configuration: Pinkel uses fixed multiband dichroic and multiband emission filters (a), Sedat uses a fixed multiband dichroic filter and a high-speed emission filter wheel (b), and Incite uses a high-speed simultaneous dichroic and emission filter switcher (c).
    High-speed filter switching provides improvements equal to doubling or quadrupling of camera quantum efficiency, with reduced risk of specimen phototoxicity.
    (All panels reproduced with permission per Creative Commons open-access licensing terms [14])
    FIGURE 1. A point source of light in the focal plane gets imaged by the microscope objective as an airy disc surrounded by a concentric ring pattern resulting from diffraction (a); when projected in three dimensions, these airy patterns (top panels) comprise PSF (lower panels; b).12, 13 The width and depth of these PSFs dictate maximize x-, y-, and z-resolution, respectively, with higher NA lenses generating smaller airy patterns and PSFs, and thus greater resolution (c).
    Ensuring that data generated by advanced imaging methods faithfully represent the biology being studied requires an understanding of key considerations.
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    Proprietary VersaChrome tunable edge filters allow users to dynamically design bandpass filter shapes by combining three simple, versatile filters.
    (Courtesy of Coherent)
    Neuroscience 2015 featured rotating poster presentations in the exhibit hall.
    Increasingly, neuroscientists are working with researchers in disciplines such as chemistry and physics. This trend has been noticed by exhibitors at the Society for Neuroscience...
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    The BUV395-3018, BV421-3824A, and BV510-3825A broadband filter sets support brilliant violet and UV dyes.
    (Image courtesy of Mary Raven, University of California, Santa Barbara)
    A cellular sample imaged using an Olympus microscope equipped with a Spectra-X LED light engine from Lumencor and Semrock's LED-DA/FI/TR/Cy5-4X-A filter set.
    LED light engines are becoming increasingly popular for fluorescence microscopy, but standard filter sets—including those packaged with the sources—typically limit their performance...
    1311prod Semrock
    The RazorEdge "E" grade product line are steep, long-wave-pass edge filters designed to provide deep blocking at the laser wavelength.

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    Additional content from IDEX Health & Science | Semrock

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    The EdgeBasic family of longpass edge filters adds 10 laser wavelengths to the 19 currently offered.
    (Image: Semrock)
    Content Dam Lfw Online Articles 2013 01 11 Band Smaller
    Rochester, NY--Semrock has begun the production of what it says is the world’s first 11-band filter, with all the bands having steep edges within a 100 nm wide spectral window...
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    Manufacturer of optical filters, Semrock, Inc. (Rochester, NY), has released their improved ultra-broadband MaxMirror.
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    The new FS01-MTiS45S-25.4 and FS01-MTiS45P-25.4, part of the PulseLine fs laser optics line, are 45° turning mirrors.
    (Courtesy Semrock)
    The user interface is shown for the free online tool from Semrock that lets you optimize the hardware for your fluorescence microscopy setup.
    Rochester, NY--Fluorescence microscope users and optical instrument designers can predetermine the optimal fluorophore, light source, detector, and optical filters through Semrock...
    FIGURE 1. A mirror designed for use inside a laser cavity has R >99.95% over a bandwidth of 500 nm (a). A mirror for cavity ring-down spectroscopy (CRDS) has R = 99.9994% at 1650 nm (b).
    With carefully controlled absorption and scattering losses, high-reflectivity, low-loss dielectric mirrors enable demanding applications such as gravitational-wave detection and...
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    The MyLight online filter modeling tool characterizes optical filters under varying theoretical conditions in real time.
    FIGURE 1: Absorption (green shaded area) and emission (pink shaded area) spectra of the three fluorophores used in the research describe fluorescence image-guided tumors and surrounding tissue. The spectra of optimal corresponding filters (green line) can be used in a FIGS microscope. Hard-coated interference filters having high (>95%) light transmission passbands and steep edges enable the collection and display of fluorescence microscopy images with high signal-to-noise ratios (for example, high image fidelity). So, high-quality optical filters are critical for removing small pieces of tumor that may otherwise go undetected.
    By enabling detection of tumor margins in real time, fluorescence image-guided surgery (FIGS) promises significant impact not only on patient outcomes, but also on healthcare ...
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    BrightLine filter sets for use with DAPI, GFP, FITC, mCherry, Texas Red, and many other fluorophores as well as sets optimized for FRET, FISH, and Qdots now include improved dichroics...
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    The VersaChrome tunable bandpass filters from Semrock offer tunability over wavelengths from 340 to 800 nm by adjusting the angle of incidence without changing spectral performance...
    Content Dam Etc Medialib New Lib Laser Focus World Online Articles 2010 09 42818
    The Penta-Sedat multiband fluorescence filter set enables imaging of five distinct fluorophores simultaneously for high-speed imaging into the near-infrared for in vivo and tissue...
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    A series of hard-coated bandpass filters are keyed to popular laser lines in the 1500 to 1600 nm region.
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    The advent of lasers as fluorescence light sources imposes new constraints and demands on the optical filters required for optimal operation of these laser-based imaging systems...
    Figure 1. A narrow laser line combined with a narrowband laser-line cleanup filter allows optimal excitation of the desired fluorophore (here green fluorescent protein, or GFP). This, combined with a steep edge filter allows almost perfect spectral efficiency for collection of weak fluorescence signals.
    Increasingly popular, total-internal-reflection-fluorescence (TIRF) microscopy systems prefer lasers for excitation because of their spectral purity and brightness.