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    • IDEX Health & Science | Semrock

    West Henrietta, NY 14586

    COMPANY OVERVIEW

    About IDEX Health & Science | Semrock

    Contact

    1180 John St
    West Henrietta, NY 14586
    United States
    https://www.idex-hs.com/semrock
    1-585-625-5000

    More Info on IDEX Health & Science | Semrock

    Manufactures high performance and reliability optical filters tailored for biotechnology and analytical instrumentation. Utilizes ion beam sputtering exclusively, making filters that will not degrade, be sensitive to humidity, or burn out. Routinely manufactures in volume, providing OEM customers with dependable supplies, and catalog customers with an extensive in-stock selection.

    Articles

    Idex Health & Science
    Optics

    Optical filter sets offer steep spectral edges

    The Semrock Avant filter set family includes the UFP/Venus, Cy3/Alexa Fluor 555, TyRed/AlexaFluor 594, Cy5.5/Alexa Fluor 680, Alexa Fluor 700, and Cy7/Alexa Fluor 750.
    Microscope design without oculars is greatly simplified (a); Etaluma’s optics module is shown (b).
    Home

    Disruptive fluorescence microscopy

    Advances in microscope components—lighting, filters, and cameras—are creating a paradigm shift in system design, with far-reaching impact.
    FIGURE 1. Multicolor switched excitation and emission light paths in a fluorescence microscope differ according to configuration: Pinkel uses fixed multiband dichroic and multiband emission filters (a), Sedat uses a fixed multiband dichroic filter and a high-speed emission filter wheel (b), and Incite uses a high-speed simultaneous dichroic and emission filter switcher (c).
    Detectors & Imaging

    Fluorescence Imaging/Microscopy: Improving fluorescence signal in time-sensitive experiments

    Prashant Prabhat, Ph.D.
    High-speed filter switching provides improvements equal to doubling or quadrupling of camera quantum efficiency, with reduced risk of specimen phototoxicity.
    (All panels reproduced with permission per Creative Commons open-access licensing terms [14])
    FIGURE 1. A point source of light in the focal plane gets imaged by the microscope objective as an airy disc surrounded by a concentric ring pattern resulting from diffraction (a); when projected in three dimensions, these airy patterns (top panels) comprise PSF (lower panels; b).12, 13 The width and depth of these PSFs dictate maximize x-, y-, and z-resolution, respectively, with higher NA lenses generating smaller airy patterns and PSFs, and thus greater resolution (c).
    Detectors & Imaging

    Optics/Advanced Microscopy: Practical considerations for advanced microscopy

    Prashant Prabhat, Ph.D.
    Ensuring that data generated by advanced imaging methods faithfully represent the biology being studied requires an understanding of key considerations.
    1601 Lfw Pro 4
    Optics

    Tunable long- and short-pass filters from Semrock adapt quickly to new fluorophores

    Proprietary VersaChrome tunable edge filters allow users to dynamically design bandpass filter shapes by combining three simple, versatile filters.
    (Courtesy of Coherent)
    Neuroscience 2015 featured rotating poster presentations in the exhibit hall.
    Research

    Neuro15 exhibitors meet exacting demands: Part 1

    Barbara Gefvert
    Increasingly, neuroscientists are working with researchers in disciplines such as chemistry and physics. This trend has been noticed by exhibitors at the Society for Neuroscience...
    1509 Lfw Pro 4
    Optics

    Brilliant violet and UV filter sets from Semrock block 355 and 405 nm laser lines

    The BUV395-3018, BV421-3824A, and BV510-3825A broadband filter sets support brilliant violet and UV dyes.
    (Image courtesy of Mary Raven, University of California, Santa Barbara)
    A cellular sample imaged using an Olympus microscope equipped with a Spectra-X LED light engine from Lumencor and Semrock's LED-DA/FI/TR/Cy5-4X-A filter set.
    Detectors & Imaging

    Fluorescence Microscopy: Optimizing the imaging performance of LED light engines

    Prashant Prabhat, Ph.D.
    LED light engines are becoming increasingly popular for fluorescence microscopy, but standard filter sets—including those packaged with the sources—typically limit their performance...
    1311prod Semrock
    Optics

    Semrock adds 9 new wavelengths to long-wave-pass edge filters

    The RazorEdge "E" grade product line are steep, long-wave-pass edge filters designed to provide deep blocking at the laser wavelength.

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    Additional content from IDEX Health & Science | Semrock

    2 Lfw 4 Semrock
    Spectroscopy

    Semrock longpass edge filters for use in Raman spectroscopy

    The EdgeBasic family of longpass edge filters adds 10 laser wavelengths to the 19 currently offered.
    (Image: Semrock)
    Content Dam Lfw Online Articles 2013 01 11 Band Smaller
    Spectroscopy

    Semrock puts 11-band optical filter into production

    John Wallace
    Rochester, NY--Semrock has begun the production of what it says is the world’s first 11-band filter, with all the bands having steep edges within a 100 nm wide spectral window...
    Semrock 073012
    Fluorescence

    Ultra-broadband optical mirror by Semrock

    Manufacturer of optical filters, Semrock, Inc. (Rochester, NY), has released their improved ultra-broadband MaxMirror.
    7 Lfw 1 Semrock
    Spectroscopy

    Semrock femtosecond laser mirrors provide reflectivity >99%

    The new FS01-MTiS45S-25.4 and FS01-MTiS45P-25.4, part of the PulseLine fs laser optics line, are 45° turning mirrors.
    (Courtesy Semrock)
    The user interface is shown for the free online tool from Semrock that lets you optimize the hardware for your fluorescence microscopy setup.
    Spectroscopy

    Free online tool from Semrock optimizes fluorescence microscopy hardware

    Gail Overton
    Rochester, NY--Fluorescence microscope users and optical instrument designers can predetermine the optimal fluorophore, light source, detector, and optical filters through Semrock...
    FIGURE 1. A mirror designed for use inside a laser cavity has R >99.95% over a bandwidth of 500 nm (a). A mirror for cavity ring-down spectroscopy (CRDS) has R = 99.9994% at 1650 nm (b).
    Test & Measurement

    OPTICS FABRICATION: High-performance mirrors excel for intracavity applications

    Neil Anderson
    With carefully controlled absorption and scattering losses, high-reflectivity, low-loss dielectric mirrors enable demanding applications such as gravitational-wave detection and...
    9 Lfw 1 Semrock
    Spectroscopy

    Online filter modeling tool from Semrock characterizes optical filters

    The MyLight online filter modeling tool characterizes optical filters under varying theoretical conditions in real time.
    FIGURE 1: Absorption (green shaded area) and emission (pink shaded area) spectra of the three fluorophores used in the research describe fluorescence image-guided tumors and surrounding tissue. The spectra of optimal corresponding filters (green line) can be used in a FIGS microscope. Hard-coated interference filters having high (>95%) light transmission passbands and steep edges enable the collection and display of fluorescence microscopy images with high signal-to-noise ratios (for example, high image fidelity). So, high-quality optical filters are critical for removing small pieces of tumor that may otherwise go undetected.
    Fluorescence

    MOLECULAR IMAGING/FLUORESCENCE-GUIDED SURGERY: Fluorescence-based molecular navigation advances cancer surgery

    Neil Anderson
    By enabling detection of tumor margins in real time, fluorescence image-guided surgery (FIGS) promises significant impact not only on patient outcomes, but also on healthcare ...
    03 Lfw 24 Semrock
    Research

    Semrock fluorescence filter sets include improved dichroics

    BrightLine filter sets for use with DAPI, GFP, FITC, mCherry, Texas Red, and many other fluorophores as well as sets optimized for FRET, FISH, and Qdots now include improved dichroics...
    Pr Versa Chrome Hires Msm
    Fluorescence

    Semrock tunable bandpass filters for fluorescence microscopy and spectroscopy

    The VersaChrome tunable bandpass filters from Semrock offer tunability over wavelengths from 340 to 800 nm by adjusting the angle of incidence without changing spectral performance...
    Content Dam Etc Medialib New Lib Laser Focus World Online Articles 2010 09 42818
    Optics

    Semrock optical filter set for five-band imaging

    The Penta-Sedat multiband fluorescence filter set enables imaging of five distinct fluorophores simultaneously for high-speed imaging into the near-infrared for in vivo and tissue...
    6 Lfw 30 Semrock
    Spectroscopy

    NIR bandpass filters from Semrock are optimized for 1.5 μm eye-safe lasers

    A series of hard-coated bandpass filters are keyed to popular laser lines in the 1500 to 1600 nm region.
    Pennwell web 500 467
    Optics

    FLUORESCENCE IMAGING: Optical filters optimize laser-based fluorescence imaging systems

    Prashant Prabhat, Ph.D.
    The advent of lasers as fluorescence light sources imposes new constraints and demands on the optical filters required for optimal operation of these laser-based imaging systems...
    Figure 1. A narrow laser line combined with a narrowband laser-line cleanup filter allows optimal excitation of the desired fluorophore (here green fluorescent protein, or GFP). This, combined with a steep edge filter allows almost perfect spectral efficiency for collection of weak fluorescence signals.
    Microscopy

    Perfecting TIRF optics

    Prashant Prabhat, Ph.D.
    Increasingly popular, total-internal-reflection-fluorescence (TIRF) microscopy systems prefer lasers for excitation because of their spectral purity and brightness.