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  • Volume 5, Issue 1
  • Volume 5, Issue 1

    Blue, green, and red spectra correspond to the first, second, and third Raman components, respectively, in spectroscopic signatures of (a) semen, (b) blood, (c) saliva, (d) sweat, and (e) vaginal fluid. Black lines are statistically obtained fluorescent components of sweat and vaginal fluid.
    Jan. 1, 2012
    The ability to analyze body fluid traces is critical for determining the key details of a crime. Now, a combination of advanced statistical methods and multidimensional Raman ...
    Robert Alfano
    Jan. 1, 2012
    During BiOS 2011, SPIE announced the launch of the Britton Chance Biomedical Optics award, to honor the memory of the prolific researcher, instructor, and leader whose contributions...
    1201bowend
    Jan. 1, 2012
    Recognizing that traumatic brain injuries need instant diagnosis followed by the proper treatment in a clinical setting, a research team has developed a near-infrared (NIR) device...
    11201bowhuberf1
    Jan. 1, 2012
    A new era has dawned in optical coherence tomography (OCT). Fourier domain mode-locking (FDML) lasers enable sustained imaging rates about 50x that of any other source, with comparable...

    More content from Volume 5, Issue 1

    (Image courtesy of Biomedical Optics Express)
    A confocal/multiphoton overlay of excised human skin shows skin autofluorescence excited by 405 nm (yellow) and ZnO nanoparticle distribution in skin (stratum corneum) excited by 770 nm (purple), with collagen-induced faint SHG signals in the dermal layer.
    Jan. 1, 2012
    An international research team has leveraged nonlinear optical microscopy to study the effect of zinc oxide (ZnO) nanoparticles in sunscreen that have raised a debate over product...
    Barbaragoode2
    Jan. 1, 2012
    “The last mile” is term the telecommunications industry uses to describe the critical gap at the end of the line that must be filled for a customer to access enhanced services...
    (Image courtesy of J. Kevin Fitzsimons, Ohio State University)
    FIGURE 1. Allen Yi and Lei Li inspect a prototype lens that can be used to create three-dimensional images.
    Jan. 1, 2012
    Innovative researchers are bringing depth into focus for three-dimensional imaging. Using a variety of tools including novel optics, light patterning, and software, they combine...
    1201bow Break Fig5
    Jan. 1, 2012
    In-vivo bioimaging is one of the applications promised by a new near-infrared (NIR) phosphor that glows for up to two weeks after a one-minute exposure to sunlight or even indoor...
    (Image courtesy of Adam Wax)
    A new spectroscopic optical coherence tomography (OCT) technique enables imaging of cellular reactions beneath the skin’s surface in true color.
    Jan. 1, 2012
    A new technique—a modified approach to optical coherence tomography (OCT) able to provide cross-sectional images of biomolecules—promises significant implications for both clinical...
    11201bowbreakf4
    Jan. 1, 2012
    A new, label-free imaging tool that tracks single-walled carbon nanotubes (SWNT) in both living cells and the bloodstream could help to boost the use of the nanotechnology in ...
    1201bowprod Lumencor
    Jan. 1, 2012
    An alternative to arc lamps, the SOLA solid-state light engine produces continuous white light from 380 to 680 nm for imaging common fluorophores and fluorescent proteins.
    Leica Microsystems will provide next-generation g-STED (gated stimulated emission depletion), licensed from the Max Planck Society and the German Cancer Research Center, in a commercial system that promises to improve resolution and contrast for continuous-wave STED while reducing laser intensity.
    Jan. 1, 2012
    As ever, it was difficult to find technology in the conference program at the Society for Neuroscience’s 2011 annual meeting (November 12–16, 2011). The presentations focused ...
    FEI’s new MAPS (Modular Automated Processing System) correlative workflow system helps researchers see both large-scale context and small-scale detail in one view.
    Jan. 1, 2012
    A session on quantitative live cell microscopy by researchers from Harvard Medical School—presented during the American Society for Cell Biology (ASCB) annual meeting (December...
    11201bowbreakf2
    Jan. 1, 2012
    You’ve heard of a lab on a chip: Now a group of researchers have developed a “lab on a bubble” approach to quickly concentrate samples in order to detect biological molecules....